Credit: Pradip Mascharak, University of California, Santa Cruz
Just Add Sunlight | Iraqibacter Treatment | Behind the Scenes
A newِ compound thatِ releases nitric oxide whenِ exposed toِ light offers a treatment toِ helpِ those infected byِ the potentially lethal bacteria Acinetobacter baumannii.
A team led byِ UC Santa Cruz chemistry professor Pradip Mascharak andِ his graduate student Brandon Heilman developed a compound that, inِ lab tests, eradicated a highly resistant strain ofِ A.
The compound consists ofِ photoactive manganese nitrosyl — whichِ releases nitric oxide whenِ itِ isِ exposed toِ light — contained inِ eitherِ a powdery silicate material (MCM-41) orِ anِ aluminosilicate material (Al-MCM-41).
There are other advantages to using nitric oxide for medical treatments:
Future plans forِ Mascharak’s team include testing theirِ treatment againstِ A.
baumannii inِ animal models.
Editor’s Note: The researchers depicted inِ Behind theِ Scenes articles haveِ beenِ supported byِ the National Science Foundation withِ funding basic research andِ education across allِ fields ofِ science andِ engineering.