Chronic Lymphocytic Leukemia Drug Treatment Shows Promise
An experimental drug, called ibrutinib, shows promise treating elderly patients withِ chronic lymphocytic leukemia, according toِ preliminary findings fromِ a phase I/II clinical trial.
Clinical trial results do not always hold up in later studies.
In theِ trials, theِ oral agent wasِ foundِ to haveِ “few side effects andِ a high one-year survival rate inِ older patients,” theِ researchers report.
Ibrutinib, alsoِ labeled PCI-32765, wasِ designed toِ target Bruton’s tyrosine kinase, a protein thatِ isِ essential forِ CLL-cell survival andِ proliferation.
Standard treatment forِ CLL involves useِ ofِ the chemotherapeutic drug fludarabine.
This story was provided by MyHealthNewsDaily, a sister site to LiveScience.
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